Stem Cell Engineering Center
Overview
The Center at UCLA provides cutting-edge services focused on generating pluripotent stem cells from patient samples; genome engineering and editing services for basic core and preclinical research; and chemical and CRISPR screenings including CRISPR mediated activation and/or inhibition of genes. Apart from its core function, the center also engages in its own independent research, optimizing published techniques to ensure reliable and reproducible methodology, and pioneering novel differentiation paradigms.
The center is dedicated to supporting work involving human stem cells in California. The HSCGEC maintains and provides well-characterized human embryonic stem (hES) cell lines and human induced pluripotent stem (iPS) cell lines.
In addition to providing all the cells, reagents, and equipment necessary for stem cell culture, the Center Director and staff provide consultation on experimental design to all researchers, and can assist in getting projects involving pluripotent cells moving quickly. The facility is centrally located on the UCLA campus, making it convenient for UCLA researchers to 'drop in' to care for their cell cultures while staying within easy reach of their home laboratories.
We are happy to provide the services of the Center to ALL researchers - both in academia and in industry.
Leadership
Services
At the UCLA Stem Cell Engineering Center, we offer stem cell generation and editing services for research and industrial purposes. Our services aim to provide researchers with the tools they need to study the complexities of the human body and develop innovative therapies. Our stem cell generation services involve the creation of induced pluripotent stem cells (iPSCs) from various cell types, including skin cells and blood cells. These iPSCs can be used to generate different types of cells for research, including neurons, heart cells, and liver cells. We offer stem cell editing services using advanced CRISPR-Cas technologies. This allows researchers to edit specific genes in stem cells, creating disease models for studying genetic disorders and developing gene therapies. Our team of experts is dedicated to providing high-quality and reliable services to our clients. We use the latest techniques and technologies to ensure that our stem cells are of the highest quality and purity, and that our editing services are precise and efficient.
IPSC Generation
Integration Free Reprogramming of Fibroblasts & PBMCs
Estimated Completion Time: 3-4 Months
For Details Contact: hyokyeongcha@mednet.ucla.edu
Stem Cell Characterization & Cell Line Quality Control
- Copy Number Variation Analysis
- Test of Pluripotency
- Pluripotency Marker IF Staining
- Epigenetic analysis of inactive X chromosome erosion in female hPSCs
- Mycoplasma Test
Estimated Completion Time: 2-8 Weeks
For Details Contact: hyokyeongcha@mednet.ucla.edu
Gene Editing
Gene Knock-Out Reporter Cell Line Generation
Estimated Completion Time: 3-4 Months
For Details Contact: data@mednet.ucla.edu
Stem Cell Derived Cells
Muscle Lineage
- hPSC-Derived Skeletal Muscle Progenitor Cells
- SMPC-to-Myotube Differentiation
Neural Lineage
- 2D Models of hPSC-Derived Neural Cell Types
- Neural Progenitors
- Astrocytes
- Excitatory Neurons
Estimated Completion Time: 1-4 Months
For Details Contact: data@mednet.ucla.edu
Cell Line Generation & Banking
- Standardized QC & Authentication
- Scalable Storage Solutions
- Fast & Reliable Retrieval
Estimated Completion Time: 1-4 Months
For Details Contact: hyokyeongcha@mednet.ucla.edu
Automated Research Platform
Coming Soon!
Estimated Completion Time: TBA
For Details Contact: data@mednet.ucla.edu