Overview

The High-Throughput Sequencing Core provides the UCLA research community with access to next-generation DNA sequencing technology. 

The technology in this Core offers capabilities including SNP mapping, RNA expression measurements, ChIP-seq and DNA methylation analysis at a genome-wide scale. 

Such capabilities enable researchers to study the regulation of thousands of genes in a single experiment, providing critical insights into the molecular biology of a cell.

The Core is located in the Terasaki Life Sciences Building, Room 3110.

Leadership

Contact

Website: Sequencing Core

Equipment

Sequencers

Illumina NovaSeq X Plus

State-of-the-art next-generation sequencing (NGS) system that offers unparalleled accuracy, speed and throughput at the lowest possible cost for RNA-seq, whole genome, whole exome and targeted DNA sequencing.

xIllumina NovaSeq X Plus Sequencer

Illumina iSeq

A flexible sequencing system with a wide range of applications that is ideal for small genome sequencing, targeted and amplicon sequencing as well as viral and microbial sequencing.

Illumina iSeq Sequencer

QC Equipment

Perkin Elmer Janus G3 liquid handler

A library preparation device programmed to execute several protocols for DNA-seq (whole genome, ChIP) and RNA-seq library preparation. 

Agilent TapeStation 4200

A quality control system used for automated electrophoresis of 1 to 96 samples. It is strongly recommended that this platform be used for all quality control steps of next-generation sequencing experiments. 

Pricing

"Service Description" Read Number Internal Rate External Rate Non-Profits External Rate
iSeq 100 2x150bp 4 million $716 $806 $838
NovaSeq X Plus - 1.5B 2x50bp 800 million $2,046 $2,433 $2,846
NovaSeq X Plus - 1.5B 1x100bp 800 million $2,046 $2,433 $2,846
NovaSeq X Plus - 1.5B 2x100bp 800 million $2,542 $3,014 $3,518
NovaSeq X Plus - 1.5B 2x150bp 800 million $2,784 $3,307 $3,866
NovaSeq X Plus - 10B 2x50bp 1.25 billion $1,556 $1,798 $2,057
NovaSeq X Plus - 10B 1x100bp 1.25 billion $1,556 $1,798 $2,057
NovaSeq X Plus - 10B 2x100bp 1.25 billion $1,850 $2,109 $2,386
NovaSeq X Plus - 10B 2x150bp 1.25 billion $1,962 $2,234 $2,524
NovaSeq X Plus - 25B 2x150bp 3.25 billion $3,168 $3,538 $3,933