Neuroscience Genomics Core (UNGC)
Semel Institute
Overview
This core facility provides advanced genomic technologies and support for neuroscience researchers at UCLA and beyond. Services include next-generation and long read sequencing, spatial transcriptomic and protein profiling and array bases methylation and genotyping services. It plays a vital role in large-scale studies of brain development, psychiatric disorders, and neurodegenerative diseases. The core enables researchers to explore how genes influence brain structure and function. Its goal is to accelerate discoveries in brain science through high-quality, accessible genomics tools.
Leadership
Services
The UCLA Neuroscience Genomics Core (UNGC) offers array based genotyping and methylation screening services NGS and long read sequencing services on the NovaSeq and Revio platforms as well as spatial imaging on the Xenium and Phenocycler platforms in the Gonda research facility on the UCLA Westwood campus. The UNGC is a not for profit academic resource available to UCLA neuroscience labs, affiliates and their collaborators. The UNGC is directed by Dr. Nelson Freimer.
Services include:
- Short read DNA/RNA library construction and sequencing
- Long read DNA/RNA template construction and sequencing on the Revio instrument
- Whole genome genotyping using all currently available Illumina arrays.
- Whole genome methylation using Illumina Methylation Epic arrays.
- Spatial transcriptomics on tissue sections on the Xenium platform.
- Protein profiling in tissue sections on the Phenocycler instrument