CNSI Electron Imaging Center for Nanosystems

(EICN)

Protein structure with atomic model (yellow sticks) overlaid on a blue electron density map.

Overview

What is Electron Microscopy?

Electron microscopy is a powerful extension of optical techniques into the sub-optical wavelength sized world. Using electrons accelerated to relativistic speeds, these microscopes can image individual atoms. Transmission electron microscopy requires a thin sample, about a micron or less, and thinner is better. It uses a variety of techniques to image and characterize samples. For example:

  • High resolution imaging can resolve individual atoms.
  • cryoEM can reveal structures and molecular interactions of biological complexes.
  • STEM imaging can differentiate atom types.
  • X-ray spectroscopy (EDX) can quantify elemental composition.
  • Tomography can resolve the 3D structure of materials and biological complexes.

Leadership

Contact

Email: EICNhelp@cnsi.ucla.edu

Website: Electron Microscopy

Services

  • Instrument Training
  • Self Usage
  • Assisted Usage
  • Data Processing

Highly experienced staff provide the necessary training and can help users address any of their complex electron imaging needs. For sample preparation and assisted usage, please email to EICNhelp@cnsi.ucla.edu for assistance.