Brain Tumor Translational Resource

Physician pointing at brain images with pen

Overview

The Brain Tumor Translational Resource (BTTR) is a biorepository and resource that supports brain tumor research at UCLA, other academic centers, brain tumor consortia, and industry. It is committed to providing its researchers and physicians with tangible brain tumor resources they may draw upon to complete their research. The BTTR provides researchers access to de-identified clinical resources and tissue on consented patients who have been diagnosed with Brain Tumors. These biospecimen resources can include blood, cell culture, stained and un-stained slides, paraffin tumor blocks, frozen tissue, DNA and RNA.   

Leadership

Contact

Email: Fausto J. Rodriguez, MD

Phone: 310-206-4111

Website: Brain Tumor Translational Resource

Submit a Request

  1. Complete the Service Request Form.
  2. Email the service request form to glucey@mednet.ucla.edu or KyuseokIm@mednet.ucla.edu.
  3. BTTR will follow up with you by email regarding your request.
  4. Please call 310-794-6769 for questions.

Equipment

Equipment is used for central and peripheral nervous system studies:

  • Multihead Light Microscopes
  • Immunohistochemistry equipment
  • CISH/FISH hybridization equipment
  • Olympus Fluorescent microscope for FISH and other fluorescence-based analyses
  • Aperio Digital Slide Scanner and image analysis software for quantification of cellular characteristics including protein expression
  • Biohazard and Fume hoods for biospecimen processing
  • -150oC electrical freezers remotely monitored with backup power and liquid nitrogen- for frozen biospecimen storage
  • Slide and formalin fixed paraffin embedded (FFPE) tissue storage cabinets
  • Labconco Lyophilizer

Services

  • Planning for tissue based studies including clinical trials
  • Brain tumor procurement from surgeries and autopsies
  • Procure control autopsy brain tissue
  • Procure lood and cerebrospinal fluid (CSF)
  • Retrieval of FFPE blocks from the pathology archives
  • Creation of FFPE blocks
  • Histology including hematoxylin and eosin stained sections and unstained sections
  • Immunohistochemistry staining and interpretation
  • Slide scanning and image analysis of whole slide images on our 30'' monitors
  • Making brain tumor tissue microarrays
  • Use of our Nanodrop spectrophotometer for quantifying nucleic acid concentrations
  • Lyophilization of biomaterials

Fees

Working with the UCLA Center for Pathology Research Services, assistance is provided in creating grant and study budgets for internal and external investigators. UCLA investigators pay a nominal fee for its services. Please contact the BTTR (smareninov@mednet.ucla.edu) for pricing information.