Crump Preclinical Imaging Technology Center
Overview
The UCLA Crump Preclinical Imaging Technology Center offers cutting edge facilities and advanced strategies for small animal imaging. The Center’s research team specializes in developing and applying advanced in vivo molecular imaging techniques to non-invasively study biological processes such as disease initiation and progression, cell trafficking, the biodistribution of small and macromolecules, the pharmacokinetics and pharmacodynamics relevant to drug development, and the research of radiopharmaceuticals.
Leadership
Services
Imaging
The Imaging Center offers microPET, microCT, SPECT, MRI, bioluminescence and fluorescence imaging modalities and complementary in vitro/ex vivo services including cell-based assays, biodistribution, digital autoradiography and dosimetry. Companion PET tracer radiochemistry and radiolabeling services are available in-house and is supported by on-campus cyclotron facilities.
Technical and analytical support are available throughout the study process:
- Initial consultation
- Experimental design and optimization
- Imaging protocols and techniques
- Post-acquisition data analysis and interpretation
- Training and staff assistance
Radiochemistry
The Radiochemistry center operates a cyclotron and a state-of-the-art radiochemistry laboratory to produce a wide variety of PET imaging tracers, and has access to additional compounds used in clinical practice and trials at UCLA via collaboration with the Ahmanson Translational Theranostics Division.
Though our primary focus is on 18F-labeled radiopharmaceuticals for PET imaging, we also work with other PET isotopes (64Cu, 68Ga, 124I, 89Zr) and therapeutic isotopes (177Lu) and have experience labeling peptides, proteins, and nanoparticles.
Pricing
Imaging Services
| Service | JCCC Rate | UCLA Rate | External Rate | Unit |
|---|---|---|---|---|
| microPET/CT | $322.91 | $430.05 | $777.10 | per hour per animal |
| microCT | $148.55 | $194.27 | $351.04 | per hour per animal |
| MRI | $176.32 | $224.47 | $405.62 | per hour |
| Optical Imaging | $108.14 | $139.31 | $251.73 | per hour |
| SPECT/CT | $239.87 | $304.42 | $550.09 | per hour |
| Image Data Analysis | $164.41 | $204.41 | $369.37 | per hour |
| Faculty Support | $242.47 | $329.14 | $594.75 | per hour |
| Staff Support | $115.02 | $142.19 | $256.93 | per hour |
| Crump Equipment | $158.24 | $213.41 | $385.64 | per hour |
| Crump Facility | $44.00 | $51.20 | $92.51 | per hour |
| Imaging Training | $274.54 | $302.32 | $546.29 | per hour |
| 3D Printing | $8.89 | $10.18 | $18.39 | per hour |
| [18F]-FDG Preparation | $151.82 | $172.02 | $418.43 | per batch |
| [18F]-NaF Preparation | $151.82 | $172.02 | $418.43 | per batch |
| Tail Vein I.V. Injection | $29.22 | $30.72 | $55.51 | per injection |
Please note:
- A standard 10-min PET/CT scan takes 25 min, including animal/equipment preparation, probe injection, and data acquisition and reconstruction. Extra acquisition time is added for longer PET scans.
- A living animal CT scan takes 25 min, including animal/equipment preparation, and data acquisition/reconstruction.
Radiochemistry Services
| Service | Internal Rate | External Rate | Unit |
|---|---|---|---|
| Prototyping | $99.88 | $201.31 | per hour |
| Machining | $30.32 | $61.10 | per hour |
| Complex Radiochem | $1,097.04 | $2,211.08 | per hour |
| Basic Radiochem | $893.71 | $1,801.27 | per hour |
| Faculty Hourly | $139.40 | $234.06 | per hour |
| Staff Hourly | $90.29 | $181.98 | per hour |
| Non-FDG Probe | $130.15 | $180.91 | per injection |
| Radiochem Facilities | $42.74 | $86.14 | per hour |
| UPLC-MS | $11.17 | $56.69 | per hour |
| Radiolabeling | $504.91 | $814.11 | per batch |
| Radioisotope | $308.50 | $1,286.43 | per batch |
| Microchips | $409.53 | $825.41 | per batch |
Please note:
All rates are approved by UCLA and are subject to change. Supplies and materials costs (e.g. precursors, radioisotopesm, etc.) needed to perform the requested radiochemistry, radiolabeling, and prototyping services will be passed on to the user at cost.