Medical Imaging

BRI Electron Microscopy Core Marianne Cilluffo mariannc@ucla.edu (310)825-9848 Room 63-377 CHS http://www.bri.ucla.edu/research/core-facilities Consultation, instruction and service in tissue preparation for LM observation; immunohistochemistry; histological stains; paraffin, frozen, LM plastic embedding and sectioning; vibratome sectioning; space and equipment use for self-service.

Crump Cyclotron and Radiochemistry Technology Center  Michael van Dam mvandam@mednet.ucla.edu (310) 206-6507 CNSI, Building 114 https://www.crump.ucla.edu/pages/techcenters Equipped for production of PET tracers, i.e., molecules labeled with radioisotopes for positron emission tomography (PET). Available services include: routine production of a continually-growing list of established tracers, development/optimization of automated synthesis protocols, and assistance with transitioning to clinical production, and the center will expand to include services for the development of novel tracers. The center is focused primarily on molecules labeled with fluorine-18, but is also experienced with positron-emitting radiometals. Facilities suitable for the development, characterization, and validation of new radiochemistry technologies are also available, and the center integrates these technologies into the tracer development and production process. The Cyclotron and Radiochemistry Technology Center is part of the Crump Institute for Molecular Imaging.

Preclinical Imaging Technology Center Jason Lee jasontlee@mednet.ucla.edu (310) 825-7137 California NanoSystems Institute, Room 2112 https://imaging.crump.ucla.edu/ Provides state-of-the-art small animal imaging. It functions both as a shared preclinical imaging resource for UCLA researchers and as a hub for emerging imaging research and technology development. The same technologies and services are also available to the larger research community including other academic institutes and industry groups through contract work. The Imaging Center, operating through its sales-and-service, offers microPET, microCT, bioluminescence and fluorescence imaging modalities and complementary in vitro/ex vivo services including cell-based assays, biodistribution, digital autoradiography and dosimetry. Companion PET tracer radiochemistry and radiolabeling services are available in-house and is supported by on-campus cyclotron facilities. Technical and analytical support are available throughout the study process:  initial consultation, experimental design and optimization, imaging protocols and techniques, post-acquisition data analysis and interpretation. Training and staff assistance The Imaging Center is part of the Crump Institute for Molecular Imaging and is supported by the expertise of its faculty members, world leaders in various imaging sciences.

Translational Research Imaging Center TRICLab@mednet.ucla.edu (310) 825-6561 CHS, BV-227 https://www.uclahealth.org/radiology/pre-clinical-services The Translational Research Imaging Center (TRIC) at UCLA is a state-of-the-art, pre-clinical and human cadaver, diagnostic and interventional imaging center. With over 25 years of expertise, our team of physicians, scientists, fellows, technologists, and veterinary staff support pre-clinical studies and imaging procedures across the field of medicine. TRIC is dedicated to the development and testing of new medical devices, imaging technologies, drug therapies as well as novel treatments.  Our dedicated staff include: Board-certified Interventional Radiologists, Board-certified Radiologists, MR Physicists, Veterinarians, Statisticians, and Experienced Research Assistants. The TRIC Lab imaging equipment and support systems include:  Magnetic Resonance Imaging (MRI) – Siemens Magnetom 3T Prisma MRI whole-body system, X-Ray Angiography – Siemens Artis Zeego Angiogram Suite with robotic C arm with 3D rotational angiography and DynaCT capabilities, Computed Tomography (CT) – Siemens Somatom Definition 64 Dual Source scanner, X-Ray Angiography – Philips Allura Xper FD-10 Angiogram Suite with floor mounted C arm with 3D rotational angiography capabilities, iU22 Philips Ultrasound system for general imaging, PACS data management system, observation and recovery suites, multi-modality 3D-image post-processing, High-Definition video integration for Telepresence video conferencing.